Smiling dog being held by woman hiking

LAVERDIA-CA1

VERDINEXOR

For pet owners who decide against chemotherapy

LAVERDIA-CA1 can give you more healthy days

When prednisone alone is not enough
LAVERDIA-CA1 prescribed with prednisone turns a hospice plan into a treatment plan designed to give you more quality time.

~1 Month

with no
treatment5

~2 Months

only high-dose
prednisone1, 2, 3

Improve lymphoma patient outcomes by 50%

The median duration of benefit is 71 days, with some patients remaining on LAVERDIA-CA1 for more than 9 months.4

2~9+ Months

LAVERDIA-CA1 with
low-dose prednisone

Improve lymphoma patient outcomes by
50%

The median duration of benefit is 71 days, with some patients remaining on LAVERDIA-CA1 for more than 9 months.4

References:
  1. Rassnick KM, et al: Survival time for dogs with previously untreated, peripheral nodal, intermediate- or large-cell lymphoma treated with prednisone alone: the Canine Lymphoma Steroid Only trial. J Am Vet Med Assoc. 2021 Jul 1;259(1):62-71.
  2. Squire RA, et al: Clinical and pathologic study of canine lymphoma: clinical staging, cell classification, and therapy. J Natl Cancer Inst. 1973 Aug;51(2):565-74.
  1. Moore AS, et al: Usefulness of chemotherapy for the treatment of very elderly dogs with multicentric lymphoma. J Am Vet Med Assoc. 2018 Apr 1;252(7):852-859.
  2. Sadowski AR, et al: Phase II study of the oral selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in dogs with lymphoma. BMC Vet Res. 2018 Aug 24;14(1):250. doi: 10.1186/ s12917-018-1587-9. PMID: 30143046; PMCID: PMC6109271.
  3. Tanovea Freedom of Information Summary: https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/11083.
Profile of Aussie/Lab looking to the side in the desertProfile of Aussie/Lab looking to the side in the desert
Icon of Heart with dots in a circle around it
Patient profile

Treatment: LAVERDIA-CA1
Plus Low-Dose Prednisone

SADIE

12 YR. OLD

AUSSIE/LAB

Diagnosis

Diffuse, large, B-cell lymphoma.
Rapid onset of symptoms including
lethargy and loss of appetite.

Pet Owner Decision

Due to concerns about quality of life for their older dog with other, pre-existing medical conditions, family opted not to pursue chemotherapy.

Outcome

Stable disease with
excellent quality of life
for 195 days.

Priced to Make Treatment
Possible for More Pet Owners

Pet owner cost

$3-10

PER DAY

DOG SIZE
$/DAY
$/MO
Small Dogs
$3
$90
Medium Dogs
$5
$150
Large Dogs
$8
$240

The cost of LAVERDIA-CA1 varied based on your dog's weight, dosage required, and duration of treatment. LAVERDIA-CA1 is prescribed and sold by veterinarians.

Icon of an oval with 4 lines radiating from it

First-in-class
Targeted Treatment

  • NOT chemotherapy
  • NOT cytotoxic
  • NOT injectable
Three Laverdia Bottles

Cancer care at home

Take-home tablet makes treatment convenient

Chemotherapy is typically an injection administered by a veterinarian, but LAVERDIA-CA1 was designed in tablet form specifically to make your dog's cancer treatment more convenient and comfortable - right at home
Weekly calendar view with a Laverdia Pill on Monday and Thursday

Twice-weekly dosing
LAVERDIA-CA1 is safe for dogs taking other medications.

Four circles with checkmarks saying 'Naïve B-cell', 'Naïve T-cell', 'Relapse B-cell' and 'Relapse T-cell'
Four circles with checkmarks saying 'Naïve B-cell', 'Naïve T-cell', 'Relapse B-cell' and 'Relapse T-cell'

Proven efficacy
LAVERDIA-CA1 treats B-cell and T-cell lymphoma, in naïve and relapse cases.

Maintain quality of life
with manageable side effects

Three Laverdia Pills Stacked Vertically

We hope LAVERDIA-CA1 gives you
more options & more time

LAVERDIA-CA1 targets XPO1s to help block the rapid replication of cancer cells. Watch how it works.

Dog being hugged by a woman on a couch

Hard on cancer, not on your dog
Across multiple clinical studies, no dogs discontinued LAVERDIA-CA1 as a result of side effects

  • Dogs maintain quality of life and continue their favorite activities.
  • Most side effects were mild or moderate and easily managed at home. Common side effects include anorexia, diarrhea, lethargy, weight loss, vomiting.
Dog walking on a trail with owner

Avoids common side effects of high-dose prednisone

  • No excessive drinking and urination
  • No loss of house training
  • No anxiety
  • No resistance to other therapies

More from the Anivive Library

Laverdia

LAVERDIA-CA1

verdinexor

Now available to
veterinarians